When John Henry Lumpkin was born on 13 June 1812, in Lexington, Oglethorpe, Georgia, United States, his father, George Lumpkin, was 24 and his mother, Sarah Matilda Pope, was 24. He married Martha Antionette McComb on 4 February 1836, in Baldwin, Georgia, United States. They were the parents of at least 1 son. He lived in Floyd Springs, Floyd, Georgia, United States in 1850. He died on 10 July 1860, in Rome, Floyd, Georgia, United States, at the age of 48, and was buried in Oak Hill Cemetery, Rome, Floyd, Georgia, United States.