When Ralph Charles Muirhead was born in March 1880, in St. Louis, St. Louis, Missouri, United States, his father, George Muirhead, was 27 and his mother, Sara Ann Crowton, was 16. He married Leona Mae Bankson on 10 August 1901, in Clayton, St. Louis, Missouri, United States. They were the parents of at least 1 son and 4 daughters. He lived in St. Louis, Missouri, United States in 1900. He died on 9 April 1913, in Lone Wolf, Kiowa, Oklahoma, United States, at the age of 33, and was buried in St. Louis, St. Louis, Missouri, United States.