When George Simeon Prestridge was born in October 1860, in Mansfield, De Soto, Louisiana, United States, his father, George Harper Prestridge, was 28 and his mother, Mary Ann Rebecca Frost, was 33. He married Alma Virginia Thompson on 24 November 1881. They were the parents of at least 4 daughters. He lived in El Dorado, Union, Arkansas, United States in 1880 and Justice Precinct 1, Angelina, Texas, United States in 1900. He died on 28 March 1931, in Shreveport, Caddo, Louisiana, United States, at the age of 70, and was buried in Greenwood Cemetery, Shreveport, Caddo, Louisiana, United States.