When Elizabeth E. Brannen was born on 27 February 1847, in Columbia, Florida, United States, her father, John Milledge Brannen Jr., was 38 and her mother, Eliza Bonnell, was 37. She married Jesse Keen on 10 August 1862, in Columbia, Florida, United States. They were the parents of at least 10 sons and 7 daughters. She lived in Polk, Florida, United States for about 5 years and Lakeland, Polk, Florida, United States for about 10 years. She died on 3 December 1933, in Plant City, Hillsborough, Florida, United States, at the age of 86, and was buried in Plant City, Hillsborough, Florida, United States.