When Samuel Barton Smoak was born on 14 April 1861, in Orangeburg, Orangeburg, South Carolina, United States, his father, Andrew Jackson Smoak, was 33 and his mother, Anna A. Bair, was 25. He married Ann Ailah Antley about 1888, in Orangeburg, South Carolina, United States. They were the parents of at least 3 sons and 1 daughter. He lived in Zion Township, Orangeburg, South Carolina, United States for about 10 years and Greensboro, Guilford, North Carolina, United States for about 8 years. He died on 2 November 1943, in Orangeburg, South Carolina, United States, at the age of 82, and was buried in Orangeburg, South Carolina, United States.