When Anna J Harlan was born on 7 May 1848, in Windsor, Henry, Missouri, United States, her father, James Harlan, was 30 and her mother, Margaret Wolf, was 26. She married Isaac Van Nuys on 27 December 1866. They were the parents of at least 1 son and 2 daughters. She lived in Franklin, Wayne, Indiana, United States in 1910 and New Garden MM, Wayne, Indiana, United States in 1920. She died on 7 October 1929, in Wayne, Indiana, United States, at the age of 81, and was buried in Bethel, Wayne, Indiana, United States.