When Margaretha Egmond was born in 1517, in Bar-le-Duc, Meuse, Lorraine, France, her father, * John (Jan) IV Count van Egmont en West-Friesland, was 18 and her mother, Françoise van Luxembourg Fiennes, Princess of Gavre, was 18. She married Duke Nicolas I de Lorraine-Lotharingen of Vaudemont Mercoeur on 1 May 1549, in Brussels, Belgium. They were the parents of at least 1 son and 3 daughters. She died on 10 March 1554, in her hometown, at the age of 37.