When Anthony Cornelius Kesler was born on 3 June 1855, in Franklin, Virginia, United States, his father, Stephan Kesler Jr, was 24 and his mother, Sophia Sink, was 24. He married Virginia Adalene Young on 25 December 1884. They were the parents of at least 5 sons and 4 daughters. He lived in Virginia, United States in 1855 and Endicott, Franklin, Virginia, United States in 1870. He died on 24 June 1926, in Ferrum, Franklin, Virginia, United States, at the age of 71.