When Luther Johnson was born on 17 October 1794, in North Carolina, United States, his father, Calvin Johnson, was 24 and his mother, Mary Francis Scott, was 24. He married Sarah Harris on 13 April 1815, in Warren, Knox, Kentucky, United States. They were the parents of at least 5 sons and 5 daughters. He lived in Simpson, Kentucky, United States in 1850. He died on 27 July 1854, in Franklin, Simpson, Kentucky, United States, at the age of 59, and was buried in Franklin, Simpson, Kentucky, United States.