When Letcher Tucker Sizemore was born in April 1846, in Clay, Kentucky, United States, his father, Willis Combs Sizemore, was 35 and his mother, Nancy Collett, was 32. He married Nancy E. Delph about 1873, in Clay, Webster, Kentucky, United States. They were the parents of at least 4 sons and 3 daughters. He lived in Magisterial District 4, Clay, Kentucky, United States in 1900 and Bell, Kentucky, United States in 1910. He died on 25 December 1933, in Leslie, Kentucky, United States, at the age of 87.