When Margaret Adams Crutcher was born on 7 November 1805, in Johnston, North Carolina, United States, her father, Thomas B Crutcher, was 35 and her mother, Catherine Bowker Smith, was 34. She married William Sanders about 1825. They were the parents of at least 5 sons and 2 daughters. She lived in Carroll, Carroll, Mississippi, United States in 1850. She died on 27 April 1851, in Carrollton, Carroll, Mississippi, United States, at the age of 45, and was buried in Carrollton, Carroll, Mississippi, United States.