When Diodate Burr was born on 29 October 1824, in Haddam, Middlesex, Connecticut, United States, his father, Daniel Burr, was 32 and his mother, Betsey Wilcox, was 31. He married Elizabeth Ann Kelsey on 14 October 1846, in Killingworth, Middlesex, Connecticut, United States. They were the parents of at least 1 son and 5 daughters. He lived in Connecticut, United States in 1870 and Bristol, Hartford, Connecticut, United States in 1910. He died on 19 December 1917, in Haddam, Middlesex, Connecticut, United States, at the age of 93, and was buried in Higganum, Haddam, Middlesex, Connecticut, United States.